How to convert Gliclazide and Gliclazide MR interchangebly?

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Good day everyone,

Encountered a question by a physician regarding Gliclazide dose conversion today.


Currently Gliclazide tablet is available in two formulations, i.e plain tablet and also Modified Release (MR) tablet.


The switching between these two formulations can be done as follows using Total Daily Dose:

Plain tablet 80mg = MR tablet 30mg


For example, patient is currently on Gliclazide 80mg BD.


Total Daily Dose = 160mg

Conversion = 160/80 x 30mg

Gliclazide MR Dose = 60mg


As simple as that !


Hope this helps those who needs it

 ; )


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